IGVF Awardees List

Characterization Awards

Awardee Institution Title
Award Number
Jay Shendure, Nadav Ahituv, Martin Kircher University of Washington, UC San Francisco, Charite Universitatsmedizin Berlin Massively parallel characterization of variants and elements impacting transcriptional regulation in dynamic cellular systems HG011966
Lea Starita, Douglas Fowler University of Washington The Center for Actionable Variant Analysis; measuring variant function at scale HG011969
Jesse Engreitz, Thomas Quertermous Stanford University Stanford Center for Connecting DNA Variants to Function and Phenotype HG011972
Marc Vidal Dana-Farber Cancer Institute Molecular phenotyping of ~100,000 coding variants across Mendelian disease genes HG011989
Gary Hon, William Kraus, Nikhil Munshi University of Texas Southwestern Medical Center Multiscale functional characterization of genomic variation in human developmental disorders HG011996
Hyejung Won, Michael Love, Karen Mohlke University of North Carolina at Chapel Hill Systematic in vivo characterization of disease-associated regulatory variants HG012003
Luca Pinello, Daniel Bauer, Guillaume Lettre, Richard Sherwood Massachusetts General Hospital, Children’s Hospital Boston, Montreal Heart Institute, Brigham and Women’s Hospital Comprehensive characterization of variants underlying heart and blood diseases with CRISPR base editing HG012010
Charles Gersbach, Gregory Crawford, Tim Reddy Duke University High-throughput functional annotation of gene regulatory elements and variants critical to complex cellular phenotypes HG012053

Mapping Awards

Awardee Institution Title
Award Number
Jason Buenrostro, Bradley Bernstein Broad Institute, Harvard University, Broad Institute, Massachusetts General Hospital A foundational resource of functional elements, TF footprints and gene regulatory interactions HG011986
Ansuman Satpathy Stanford University Single-cell Mapping Center for Human Regulatory Elements and Gene Activity HG012076
Seyed Mortazavi, Barbara Wold UC Irvine, California Institute of Technology Center for Mouse Genomic Variation at Single Cell Resolution HG012077

Predictive Modeling Awards

Awardee Institution Title
Award Number
Alan Boyle University of Michigan Predicting the impact of genomic variation on cellular states HG011952
Andrew S. Allen, Shayan Mukherjee, Charles D. Page Jr. Duke University Design, prediction, and prioritization of systematic perturbations of the human genome HG011967
Soumya Raychaudhuri, Alkes Price, Shamil Sunyaev Brigham and Women’s Hospital, Harvard School of Public Health, Brigham and Women’s Hospital Predicting the impact of genetic variants, genes and pathways on human disease HG012009
Predrag Radivojac Northeastern University Supporting IGVF by modeling genetics, function, and phenotype with machine learning HG012022
Mark Craven University of Wisconsin Linking variants to multi-scale phenotypes via a synthesis of subnetwork inference and deep learning HG012039
Zhiping Weng, Manuel Garber, Xihong Lin University of Massachusetts Medical School, University of Massachusetts Medical School, Harvard School of Public Health Predictive modeling of the functional and phenotypic impacts of genetic variants HG012064
Anshul Kundaje Stanford University Predicting context-specific molecular and phenotypic effects of genetic variation through the lens of the cis-regulatory code HG012069

Network Awards

Awardee Institution Title
Award Number
Harinder Singh, Nidhi Sahni, Jishnu Das The University of Pittsburgh, The University of Texas MD Anderson Cancer Center, University of Pittsburgh Linking genome variation to transcriptional network dynamics in human B cells HG012041
Hao Wu, Sreeram Kannan, Hongjun Song University of Pennsylvania Defining causal roles of genomic variants on gene regulatory networks with spatiotemporally-resolved single-cell multiomics HG012047
Danwei Huangfu, Michael Beer, Anna-Katerina Hadjantonakis Sloan Kettering Institute for Cancer Research, Johns Hopkins University School of Medicine, Sloan Kettering Institute for Cancer Research Genomic control of gene regulatory networks governing early human lineage decisions HG012051
Maike Sander, Hannah Carter, Kyle Gaulton, Bing Ren UC San Diego The impact of genomic variation on environment-induced changes in pancreatic beta-cell states HG012059
Chongyuan Luo, Kathrin Plath, Noah Zaitlen UC Los Angeles Leveraging genetic variation to dissect gene regulatory networks of reprogramming to pluripotency HG012079
Christina Leslie, Alexander Rudensky Sloan Kettering Institute for Cancer Research Deciphering the genomics of gene network regulation of T cell and fibroblast states in autoimmune inflammation HG012103

Data and Administrative Coordinating Center Awards

Awardee Institution Title
Award Number
J. Michael Cherry, Mark Gerstein Stanford University, Yale University A Data and Administrative Coordinating Center for the Impact of Genomic Variation on Function Consortium HG012012
Ting Wang, Feng Yue Washington University Saint Louis, Northwestern University WashU-Northwestern Genomic Variation and Function Data and Administrative Coordinating Center HG012070